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Overview on acute-on-chronic liver failure

Jing Zhang,Shan Gao,Zhongping Duan,Ke-Qin Hu

Frontiers of Medicine 2016, Volume 10, Issue 1, Pages 1-17 doi: 10.1007/s11684-016-0439-x

Abstract:

Liver failure (LF) is defined as severe dysfunction in hepatic synthesis, detoxification, and metabolism

Keywords： liver failure chronic liver failure acute-on-chronic liver failure diagnosis prognosis treatment

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The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortalityof patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Frontiers of Medicine 2021, Volume 15, Issue 3, Pages 495-505 doi: 10.1007/s11684-020-0790-9

Abstract: explore the effect and mechanisms of the treatment plan of “traditional Chinese medicine (TCM) regulating liverA total of 457 patients with HBV-related liver failure were retrospectively collected.In addition, there were significant differences in the expression of several cytokines related to liverRLR treatment can decrease jaundice, improve liver function, and significantly reduce the mortality inpatients with HBV-related liver failure.

Keywords： hepatitis B virus-related liver failure traditional Chinese medicine liver regeneration liver regeneration

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Comprehensive treatment of acute-on-chronic liver failure in a patient with hepatitis B: a case report

Lei Li,Yimei Liu,Tiancheng Luo,Jian Zhou,Yingyong Hou,Xizhong Shen,Jiyao Wang

Frontiers of Medicine 2014, Volume 8, Issue 2, Pages 250-253 doi: 10.1007/s11684-014-0333-3

Abstract:

The clinical data of a patient with acute-on-chronic liver failure were analyzed retrospectively.His liver function deteriorated, yielding Child-Pugh grade C and reaching a model for end-stage liverperiod; this condition was complicated with highly active variceal bleeding and coagulation system failurePiggyback orthotopic liver transplantation was performed as the final treatment.

Keywords： acute-on-chronic liver failure submassive necrosis viral hepatitis B esophageal variceal bleeding liver

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Assessment of liver volume variation to evaluate liver function

Cong Tong, Xinsen Xu, Chang Liu, Tianzheng Zhang, Kai Qu

Frontiers of Medicine 2012, Volume 6, Issue 4, Pages 421-427 doi: 10.1007/s11684-012-0223-5

Abstract:

In order to assess the value of liver volumetry in cirrhosis and acute liver failure (ALF) patientsto get a regression formula for standard liver volume (SLV) and BSA.It turned out that the mean liver volume of the control group was 1 058±337 cm³.Child A, B level was not reduced, but in Child C level it was significantly reduced with the lowest liverIn conclusion, the CTLV/SLV ratio, which reflects liver volume variations, correlates well with the liver

Keywords： liver volume variation cirrhosis acute liver failure (ALF)

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Bioartificial liver devices: Perspectives on the state of the art

Yi-Tao DING, MM, Xiao-Lei SHI, MD

Frontiers of Medicine 2011, Volume 5, Issue 1, Pages 15-19 doi: 10.1007/s11684-010-0110-x

Abstract:

Acute liver failure remains a significant cause of morbidity and mortality.Bioartificial liver (BAL) devices have been in development for more than 20 years.Such devices aim to temporarily take over the metabolic and excretory functions of the liver until thepatients’ own liver has recovered or a donor liver becomes available for transplant.failure, and may also be a bridge to liver transplantation.

Keywords： acute liver failure bioartificial livers hepatocyte bioreactor

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Intra-abdominal hypertension is an independent cause of acute renal failure after orthotopic liver transplantation

SHU Ming, PENG Chenghong, CHEN Hao, SHEN Boyong, ZHOU Guangwen, SHEN Chuan, LI Hongwei

Frontiers of Medicine 2007, Volume 1, Issue 2, Pages 167-172 doi: 10.1007/s11684-007-0031-5

Abstract: An independent association between acute renal failure (ARF) and intra-abdominal hypertension (IAH) afterliver transplantation has not been established previously.This study involved 62 subjects who underwent liver transplantation.IAH impaired renal function and was an independent risk factor for ARF after liver transplantation.

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Severe hepatoxicity caused by aspirin overdose: a case report

Zhuping Cao,Shiqi Liu,Jianhua Niu,Bing Wei,Jie Xu

Frontiers of Medicine 2015, Volume 9, Issue 3, Pages 388-391 doi: 10.1007/s11684-015-0398-7

Abstract: Two years later, the patient died of chronic liver failure.

Keywords： aspirin side effects liver failure

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Gut Microbiota-Controlled Tryptophan Metabolism Improves D-Gal/LPS-Induced Acute Liver Failure in C57BL Article

Zhipeng Zheng, Li Wu, Yuqiu Han, Jun Chen, Shuai Zhu, Yuanyuan Yao, Baohong Wang, Lanjuan Li

Engineering 2022, Volume 14, Issue 7, Pages 134-146 doi: 10.1016/j.eng.2020.12.013

Abstract:

Acute liver failure (ALF) has an abrupt onset with a frequently fatal outcome.Previous studies have found that oral antibiotics prevent drug-induced liver injury in animal experimentssequencing showed that inflammatory responses were inhibited and metabolic pathways were upregulated in the liver

Keywords： Gut microbiota Antibiotic Tryptophan Kynurenine Aryl hydrocarbon receptor Acute liver failure

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Partial liver transplantation

Nianqiao GONG, Xiaoping CHEN

Frontiers of Medicine 2011, Volume 5, Issue 1, Pages 1-7 doi: 10.1007/s11684-010-0105-7

Abstract:

Partial liver transplantation, including reduced-size liver transplantation, split liver transplantation, and living donor liver transplantation, has been developed with several innovative techniques becauseSplit liver transplantation provides chances to two or even more recipients when only one liver graftBefore surgery, a series of donor evaluations—including anatomical, liver volume, and liver functionAt different recipient conditions, auxiliary liver transplantation and auxiliary partial orthotopic liver

Keywords： partial liver transplantation reduced-size liver transplantation split liver transplantation living donorliver transplantation

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γδ T cells in liver diseases

Xuefu Wang, Zhigang Tian

Frontiers of Medicine 2018, Volume 12, Issue 3, Pages 262-268 doi: 10.1007/s11684-017-0584-x

Abstract: γδ T cells are enriched in the liver and exhibit liver-specific features.fatty liver disease, autoimmune hepatitis, liver fibrosis and cirrhosis, and liver cancer and regenerationWe believe that determining the properties and functions of γδ T cells in liver diseasesenhances our understanding of the pathogenesis of liver diseases and is useful for the design of novelγδ T cell-based therapeutic regimens for liver diseases.

Keywords： γδT cells liver infection non-alcoholic fatty liver disease autoimmune hepatitis liver fibrosis and cirrhosis liver cancer liver regeneration

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NKT cells in liver diseases

Shasha Zhu, Huimin Zhang, Li Bai

Frontiers of Medicine 2018, Volume 12, Issue 3, Pages 249-261 doi: 10.1007/s11684-018-0622-3

Abstract: innate-like and tissue-resident lymphocytes, which recognize lipid antigens and are enriched in the livernatural killer T cells and their roles in hepatitis B virus and hepatitis C virus infection, autoimmune liverdiseases, alcoholic liver disease, nonalcoholic fatty liver disease, and hepatocellular carcinoma.and indicate the dynamic alteration in the role of natural killer T cells during the progression of liver

Keywords： natural killer T cells hepatitis B virus and hepatitis C virus infection autoimmune liver diseases alcoholicliver disease nonalcoholic fatty liver disease hepatocellular carcinoma

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Integrated management of cardiac failure: the cardiac failure clinic

Daniel LOISANCE

Frontiers of Medicine 2011, Volume 5, Issue 1, Pages 20-25 doi: 10.1007/s11684-011-0106-1

Abstract:

The prevalence of the risk factors and the risk of cardiac failure are both increasing in China.The wide range of clinical presentations of cardiac failure (acute or chronic) and of therapeutic approaches

Keywords： cardiac failure cardiac transplantation mechanical circulatory support

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Natural killer cells in liver diseases

Meijuan Zheng, Haoyu Sun, Zhigang Tian

Frontiers of Medicine 2018, Volume 12, Issue 3, Pages 269-279 doi: 10.1007/s11684-018-0621-4

Abstract:

The liver has been characterized as a frontline lymphoid organ with complex immunological featuressuch as liver immunity and liver tolerance.Liver tolerance plays an important role in liver diseases including acute inflammation, chronic infectionThe liver contains a large proportion of natural killer (NK) cells, which exhibit heterogeneity in phenotypicUnder the setting of liver diseases, NK cells are of great importance for stimulating or inhibiting immune

Keywords： natural killer cell phenotype immune activation immune tolerance liver diseases

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Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Frontiers of Medicine 2018, Volume 12, Issue 2, Pages 123-129 doi: 10.1007/s11684-017-0563-2

Abstract:

Liver transplantation is a conventional treatment for terminal stage liver diseases.Intestinal barrier destruction is widely observed among patients receiving liver transplant and sufferingThis article reviews the research progress for gut microbial alterations and liver transplantation.microbial alteration and the prediction of possible injuries utilizing microbial alteration during liverand offer a hypothesis on the utilization of microbial alteration in liver transplantation.

Keywords： gut microbial balance liver transplantation ischemia–reperfusion acute rejection

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Molecular mechanisms of fatty liver in obesity

Lixia Gan,Wei Xiang,Bin Xie,Liqing Yu

Frontiers of Medicine 2015, Volume 9, Issue 3, Pages 275-287 doi: 10.1007/s11684-015-0410-2

Abstract:

Nonalcoholic fatty liver disease (NAFLD) covers a spectrum of liver disorders ranging from simplesteatosis, which is characterized by excessive accumulation of triglyceride-rich lipid droplets in the liverAccumulating evidence supports that dysregulation of adipose lipolysis and liver de novo&

Keywords： nonalcoholic fatty liver disease insulin resistance obesity

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Title Author Date Type Operation

Overview on acute-on-chronic liver failure

Jing Zhang,Shan Gao,Zhongping Duan,Ke-Qin Hu

Journal Article

The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortalityof patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Journal Article

Comprehensive treatment of acute-on-chronic liver failure in a patient with hepatitis B: a case report

Lei Li,Yimei Liu,Tiancheng Luo,Jian Zhou,Yingyong Hou,Xizhong Shen,Jiyao Wang

Journal Article

Assessment of liver volume variation to evaluate liver function

Cong Tong, Xinsen Xu, Chang Liu, Tianzheng Zhang, Kai Qu

Journal Article

Bioartificial liver devices: Perspectives on the state of the art

Yi-Tao DING, MM, Xiao-Lei SHI, MD

Journal Article

Intra-abdominal hypertension is an independent cause of acute renal failure after orthotopic liver transplantation